dGH SCREEN™ Unbiased Assay Designed to Monitor Structural Variants throughout the Genome
With dGH SCREEN™, researchers are able to track and localize a wide variety of chromosomal rearrangements within a 10kb limit of detection. In addition to being an unbiased tool for the detection of structural variants throughout the genome SCREEN™ offers High Resolution Analysis of DNA repair activity by monitoring hallmarks of genomic instability, including sister chromatid changes.
Application Benefits of SCREEN™:
- Exchange Events & Orientation Events
- Chromosomal Gain & Loss Events
- Monitoring Cellular Engineering Outcomes
- Orthogonal Data for Sequencing
- Structural Integrity QC
- Variant Discovery
- Genomic Stability Assessment
This analysis produces vast amounts of rearrangement data which can be used to create stability and structural variance profiles for complex and heterogeneous cell populations, making dGH SCREEN one of the most comprehensive and robust karyographic assays available.