dGH SCREEN™ Targeted Assay Services
dGH SCREEN™ Assay Services

Our single cell assay, dGH SCREEN™ is designed to monitor structural variants throughout the genome. By utilizing patented directional Genomic Hybridization™ technology combined with multiplex fluorescence labeling, researchers can track and localize a wide variety of chromosomal rearrangements with a limit of detection as low as 5kb. By utilizing our chromosome paints and creating a 5 color assay, you will receive high resolution analysis of DNA repair activity by monitoring hallmarks of genomic instability, including sister chromatid changes.

Overview of dGH SCREEN™ Assay Services:

  • Detection of exchange events including reciprocal, balanced and allelic translocations;
  • Orientation events like inversions and sister chromatid exchanges;
  • Chromosomal Gain & Loss Events including sister chromatid fusions, dicentrics/acentrics, fragmentation/chromothrypsis, polypoidy and aneuploidy;
  • Cellular engineering outcomes: genome-wide, cell-by-cell and chromosome-by-chromosome assessment of structure, pre- and post-modification
  • Orthogonal data for sequencing: genome-wide, confirmatory data regarding rearrangements predicted with long read and other NGS analyses;
  • Structural integrity QC: a straightforward yardstick by which to measure the relative stability of cell lines, or to screen and compare candidate cell lines, based on total genomic structural variation metrics;
  • Genomic Stability Assessment: Track persistence of variants over time, passages, process variable changes, etc.
  • Variant discovery: discover previously unknown mutations by de novo assessment of single cells from patient sub-types;

dGH SCREEN™ analysis produces vast amounts of rearrangement data which can be used to create stability and structural variance profiles for complex and heterogeneous cell populations, making dGH SCREEN™ one of the most comprehensive and robust karyographic assays available.

Loading...

Ordering Information

SKU
PRODUCTS
LIST PRICE
SCR-001 SCREEN Adherent/Suspension Culture Development: Thaw, recovery, and harvest optimization $1,200.00
SCR-002 SCREEN Assay Execution and Analysis: Imaging and scoring for 50 spreads/sample $5,500.00
SCR-003 SCREEN Assay Execution and Analysis: Imaging and scoring for 20 spreads/sample $3,300.00
SCR-004 SCREEN Assay Execution and Analysis: Imaging and scoring for 100 spreads/sample $9,900.00
SCR-005 SCREEN T-Cell Culture Development: Thaw, recovery, and harvest optimization $1,300.00
SCR-006 SCREEN IPSC Cell Culture Development: Thaw, recovery, and harvest optimization $1,400.00
SCR-007 SCREEN Whole Blood Culture Development: Thaw, recovery, and harvest optimization $1,000.00
SCR-008 SCREEN Adherent/Suspension Metaphase Prep and Harvest $1,200.00
SCR-009 SCREEN T Cells Metaphase Prep and Harvest $1,300.00
SCR-010 SCREEN IPSC Metaphase Prep and Harvest $1,400.00
SCR-011 SCREEN Whole Blood Metaphase Prep and Harvest $1,000.00

Please fill out the form below to inquire about dGH SCREEN™ assays

INQUIRE

RESOURCES

DGH SCREEN™ DATA SHEET
DGH SCREEN™ Assay Services Overview
Geno Toxicity and Genomic Instability Datasheet
Microscope Assay Specifications datasheet
dGH SCREEN™ Sample Report
Sample Gene Editing Report

PRODUCTS

Centromere Pinpoint FISH™ Probes
subTelomere Pinpoint FISH™ Probes
ONCOLOGY PINPOINT FISH™ PROBES
PINPOINT FISH™ TP53/CEP17 KIT
HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
dGH™ CELL PREP KIT
FISH BUFFERS

SERVICES

Cell Culture Services
G-Banding
DGH IN-SITE™ TARGETED ASSAY SERVICES
DGH SCREEN™ UNBIASED ASSAY SERVICES
PINPOINT FISH™ ASSAY SERVICES