dGH in-Site™
Targeted assays.
It’s a big genome. Don’t play hide and seek.
With dGH in-Site researchers can track sequences as small as 2kb, throughout the genome, one cell at a time.
Chromosomes of CAR-T cell following lentivirus-mediated editing hybridized with control paint (chr1, red) and transgene probe (yellow) with arrows pointing to two centromeres in a dicentric chromosome.
What is dGH in-Site?
By pairing KromaTiD’s synthetic, single-stranded probes with cutting-edge imaging analysis and cell preparation methods, researchers can see what’s going on in their cells like never before.
- Whole-genome DNA tracking, including edit sites or transgenes as small as 2kb
- On and off-target analysis of integrants or edits
- Direct visualization of rearrangements including translocations, inversions and copy number variants
- Cell-by-cell data for complex or heterogeneous populations