dGH in-Site™
Visualize single-cell genome data in an entirely new way.
Spotlight Genomic Sequences with
dGH in-Site™
With dGH in-Site, researchers can target sequences as small as 2kb across the entire genome, one cell at a time.
Chromosomes of CAR-T cell following lentivirus-mediated editing hybridized with control paint (chr1, red) and transgene probe (yellow) with arrows pointing to two centromeres in a dicentric chromosome.
What is dGH in-Site?
By pairing KromaTiD’s synthetic, single-stranded oligonucleotide probes with innovative imaging analysis and cell preparation methods, researchers can see single cell genome data in an entirely new way.
- Whole-genome DNA tracking, including edit sites and/or transgenes as small as 2kb
- Enumeration of on- and off-target edits
- Direct visualization of rearrangements including translocations, inversions, and copy number variants
- Cell-by-cell data for complex or heterogeneous populations