dGH SCREEN™
Genomic stability assays & chromatid paints.
Don’t let sequencing leave
you in the dark.
Stop guessing what’s going on in the rest of the genome.
It’s time to see for yourself.
dGH SCREEN karyogram of a triple-edited T cell displaying multiple inversions and a dicentric derivative composed of material from chromosomes 15 and 16.
What is dGH SCREEN?
The dGH SCREEN assay provides per-chromosome attribution of inter- and intra-chromosomal structural events including inversions, translocations, aneuploidy (gain and loss), insertions, centromere abnormalities and complex events across a sample. It is a dGH paint-combination assay for all 24 human chromosomes.
The assay is composed of unique sequence, high-density (HD) dGH chromosome paints in five color panels such that chromosomes painted in the same color can be differentiated by size, shape, and centromere position.
- dGH probes spanning every chromosome provide unbiased coverage of the entire genome
- Direct visualization of all types of structural rearrangements including translocations, inversions, sister chromatid exchanges and copy number variants
- Chromosome size and color groupings enable identification of chromosomes involved in rearrangement event(s)
- Cell-by-cell data for complex or heterogeneous populations
- Measure structural variants in select chromosomes of interest for a targeted data set.