iPSC’s (induced Pluripotent Stem Cells) are an important cell for cancer studies. Human embryonic stem cells have two important properties; self-renewal (pluripotent) and an ability to differentiate into many other specialized cells. By reprogramming the adult specialized cells you can turn those cells into iSPC’s. Four genes were added to a mouse skin cell and it created iSPC’s, and less than four can turn a human cell into an iSPC. These iSPC’s are put into a renewal state (pluripotent) and then used to discover early biomarkers and therapeutic approaches towards cancer and disease. Biomarkers are indicative of early cancer stages and provide researchers an in-depth look at how the cells are reacting to whatever biomarker they see. Many diseases are not found into later stages such as pancreatic cancer, and melanoma. These cells provide researchers the ability to find these biomarkers, and catch disease and cancers in their early stages. Following being therapeutic discovery, where therapies are used to treat the cells and can treat these cancers early on, before the later stages develop. As cells divide and multiply they can spread the cancer and diseases quickly if not caught early on. This s a novel research tool for immunotherapy and provides answers to questions most researchers have been searching for decade after decade. If you can find the biomarker and begin to develop a therapy against it, then you can see how the cell responds to each therapy. They will either repair or not. Many people in clinical trials are waiting for these therapies to treat an often life threatening disease, and assist in a longer lifespan. By studying these iPSC’s and using a certain immunotherapy, it allows a patient on the other end to be treated with the therapies that will work for them.
For more information on how KromaTiD can assist in your iSPC research visit us at: kromatid.com