CAR-T cell
dGH in-Site™ CAR-T Probes

Detect structural rearrangements at CAR-T loci of interest associated with gene editing and cellular engineering modifications.

Directly Visualize the Structure of on- and off-target DNA Edit Sites and Mapping of Transgene Insertions Anywhere in the Genome. 

dGH in-Site™ Probes provide single-cell, in situ hybridization assays. dGH data enables detection of low-level abnormalities missed in sequencing data from pooled DNA samples, and provides data orthogonal and complementary to sequencing and G-bandingdGH is able to detect smaller inversions than FISH, and provides you with a comprehensive data set for your cellular engineering methods to provide genomic safety and stability data for analysis. 

Key features of dGH™ technology:

  • Ultra-high resolution, as low as 2 kb.
  • High signal-to-noise ratio boosts scoring confidence and efficiency.
  • Cell preparation yields single-stranded metaphase chromosomes. 
  • Single-stranded fluorescent probes provide direct visualization of editing outcomes including orientation and balanced/unbalanced structural variants.
  • Custom Probes available for any gene target and fluorophore. 

Still have questions? Chat with us by using our chat box, we are available 9a-5p MST!

*For use in metaphase cells fixed with 3:1 MeOH:Acetic acid.

Order Below

Showing 1 - 12 out of 12

Page 1 out of 1

Product Locus Product Contents Price Quantity Add to Cart
dGH™ Probe TRAC TexRed
dGH™ Probe B2M 6-FAM/Spectrum Green
dGH™ Standard Hybridization Buffer
$1,500.00
dGH™ Probe TRAC TexRed
dGH™ Probe B2M 6-FAM/Spectrum Green
dGH™ Standard Hybridization Buffer
dGH™ Cell Prep Reagent 250 µL
Demecolcine Solution 2.5 ml
dGH™ Image Analysis Support
$2,799.00
14q11.2
$800.00
2q37.3
$800.00
15q21.1
$800.00
16p13.13
$800.00
$6,250.00
$800.00
$10.00
$10.00
$1,000.00
$500.00