dGH in-Site™ CAR-T Probes
Detect structural rearrangements at CAR-T loci of interest associated with gene editing and cellular engineering modifications.
Directly Visualize the Structure of on- and off-target DNA Edit Sites and Mapping of Transgene Insertions Anywhere in the Genome.
dGH in-Site™ Probes provide single-cell, in situ hybridization assays. dGH data enables detection of low-level abnormalities missed in sequencing data from pooled DNA samples, and provides data orthogonal and complementary to sequencing and G-banding. dGH is able to detect smaller inversions than FISH, and provides you with a comprehensive data set for your cellular engineering methods to provide genomic safety and stability data for analysis.
Key features of dGH™ technology:
- Ultra-high resolution, as low as 2 kb.
- High signal-to-noise ratio boosts scoring confidence and efficiency.
- Cell preparation yields single-stranded metaphase chromosomes.
- Single-stranded fluorescent probes provide direct visualization of editing outcomes including orientation and balanced/unbalanced structural variants.
- Custom Probes available for any gene target and fluorophore.
Still have questions? Chat with us by using our chat box, we are available 9a-5p MST!
*For use in metaphase cells fixed with 3:1 MeOH:Acetic acid.
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Showing 1 - 12 out of 12
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| Product | Locus | Product Contents | Price | Quantity | Add to Cart |
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dGH™ Probe TRAC TexRed
dGH™ Probe B2M 6-FAM/Spectrum Green dGH™ Standard Hybridization Buffer |
$1,500.00
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dGH™ Probe TRAC TexRed
dGH™ Probe B2M 6-FAM/Spectrum Green dGH™ Standard Hybridization Buffer dGH™ Cell Prep Reagent 250 µL Demecolcine Solution 2.5 ml dGH™ Image Analysis Support |
$2,799.00
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14q11.2
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$800.00
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2q37.3
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$800.00
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15q21.1
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$800.00
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16p13.13
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$800.00
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$6,250.00
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$800.00
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$10.00
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$10.00
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$1,000.00
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$500.00
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