Unlocking Genomic Analysis for Structural Variant Detection in Cancer
The ability to detect low frequency, heterogenous structural variants within a solid or liquid tumor sample is crucial for understanding the underlying dynamics of oncogenic drivers and investigating the role played by mechanisms such as genomic instability, chemoresistance, copy number variation and DNA amplification, to name a few.
Both our single-cell, directional Genomic Hybridization (dGH™) and Pinpoint FISH™ assays are innovative and powerful approaches to visualize and map the structure of cancer genomes.
dGH™ probes and assays are strand-specific, cytogenomic tools that identify specific oncogenic events with industry-high resolution, providing unprecedented insights into the initiation, propagation, and evolution of cancers. The bioinformatic design and high signal-to-noise ratio of Pinpoint FISH probes and assays make them perfect complementary tools to dGH analysis.