
Radiation Biodosimetry
Visualize and Quantify Inversions with dGH SCREEN™
dGH SCREEN™, the original KromaTiD assay, was utilized by NASA in the “Twin’s Study” to measure DNA damage from deep space radiation. NASA’s first foray into “omics” research represented a unique opportunity to develop a next-generation personalized medicine approach to monitoring the health of astronauts.
Today our dGH SCREEN™ platform is still being used by NASA to assess structural rearrangements in the genomes of their best and brightest. dGH SCREEN™ technology is a unique single stranded design allows researchers to visualize and quantify inversions as an inherently more stable biodosimeter than dicentrics, which enables them to obtain data much longer after a radiation event. In addition to greater stability, inversions occur with lower background frequency than other symmetrical aberrations such as translocations, providing fewer false positives and more reliable data.