TP53/CEP17 Pinpoint FISH™ Probe
The Pinpoint FISH™ TP53/CEP17 probe kit is a synthetic oligonucleotide-based assay. With low cross-hybridization instances and signals that are reliably bright, our FISH probes make numerical and structural abnormalities easy to detect. The increased signal-to-noise ratio relative to BAC FISH probes means quicker analysis and higher-confidence results.
TP53, 17p13. Red
The probe mix consists of a 500kb TP53 probe, labeled in red, that covers the whole TP53 gene and the flanking regions. The probe mix also contains a control probe targeting the 17q11.1-q11.2 region labeled in green.
The Pinpoint FISH™ TP53/CEP 17 FISH Probe Kit is intended to detect the copy number of the LSI TP53 probe target located at 17p13 and of the 17q11.1-q11.2 locus. The CEP 17 probe is a control probe which hybridizes to the 17q11.1-q11.2 locus.
KromaTiD’s Pinpoint FISH™ TP53/CEP17 Kit is ideal for the following FISH applications:
- Screening of hematological and other cell suspension samples
- Testing of indications including, CLL, PLL, LPD and myeloma
Pinpoint FISH™ probes routinely detect targets smaller than BAC FISH probes. For labs that currently run FISH on hematological and other suspension cell samples, the TP53/CEP17 Assay Kit uses standard FISH consumables and standard FISH equipment. Probes have been tested in combination assays with BAC FISH probes.
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