TP53, 17p13. Red
The probe mix consists of a 500kb TP53 probe, labeled in red, that covers the whole TP53 gene and the flanking regions. The probe mix also contains a control probe targeting the 17q11.1-q11.2 region labeled in green.
The Pinpoint FISH™ TP53/CEP 17 FISH Probe Kit is intended to detect the copy number of the LSI TP53 probe target located at 17p13 and of the 17q11.1-q11.2 locus. The CEP 17 probe is a control probe which hybridizes to the 17q11.1-q11.2 locus.
KromaTiD’s Pinpoint FISH™ TP53/CEP17 Kit is ideal for the following FISH applications:
- Screening of hematological and other cell suspension samples
- Testing of indications including, CLL, PLL, LPD and myeloma
Pinpoint FISH™ probes routinely detect targets smaller than BAC FISH probes. For labs that currently run FISH on hematological and other suspension cell samples, the TP53/CEP17 Assay Kit uses standard FISH consumables and standard FISH equipment. Probes have been tested in combination assays with BAC FISH probes.