dGH in-Site™ Assays
Track your genome editing outcomes and get a comprehensive analysis of your on- and off-target effects.
Above Fig.: dGH in-Site™ assay in an edited iPSC line cell with no off-target insertions. Target site bracketing probes in green and insert probe in yellow zoomed in and expanded on the right. Results from this sample indicated that 6% of cells had no off-target insertions.
Detect and Differentiate any Genomic Target Including Inversions Starting at 2kb.
For gene therapy applications analysis of specific edits or engineered cell lines are measured for any structural variation involved with the edit site, including rearrangements involving on-target and off-target loci. use dGH in-Site™ to track and locate transgene integration throughout the genome.
Key benefits of dGH in-Site™ assays:
- Track transgenes and define Insertional Copy Number (ICN).
- On- and off-target Insertional Copy Number (ICN).
- Characterize structural variations from mis-repair of your edit sites.
- Distribution of integrations on both a single cell and genome-wide basis.
- Customized to meet individual genomic structural research needs unique to your project.
- We can design 1-4 probe assays, including assay execution and analysis as many as 600 cells per sample
- Metaphase prep and harvest, along with cell culture development is available.
Contact us below to receive a quote on a custom project to suit your needs!
Catalog Number |
Services |
Cost |
|---|---|---|
| DGH-002 | Standard Probe Production: Design and verification of standard probes | $1,375 |
| DGH-007 | Custom Probe Production: Design and verification of custom probes | $6,250 |
| DGH-009 | T-Cell Culture Development: Thaw, recovery, and harvest optimization | $1,500 |
| DGH-012 | T-Cell Metaphase Prep and Harvest | $1,500 |
| DGH-010 | IPSC Cell Culture Development: Thaw, recovery, and harvest optimization | $1,625 |
| DGH-013 | IPSC Metaphase Prep and Harvest | $1,625 |
| DGH-011 | Whole Blood Culture Development: Thaw, recovery, and harvest optimization | $1,125 |
| DGH-014 | Whole Blood Metaphase Prep and Harvest | $1,125 |
| DGH-029 | NK Cell Culture Development: Thaw, recovery, and harvest optimization | $1,500 |
| DGH-024 | NK Cells Metaphase Prep and Harvest | $1,500 |
| DGH-030 | 1 probe assay, 20 cells per sample, Assay Execution and Analysis | $1,219 |
| DGH-027 | 1 probe assay, 50 cells per sample, Assay Execution and Analysis | $1,828 |
| DGH-025 | 1 probe assay, 100 cells per sample, Assay Execution and Analysis | $2,742 |
| DGH-006 | 1 probe assay, 200 cells per sample, Assay Execution and Analysis | $4,113 |
| DGH-054 | 1 probe assay, 400 cells per sample, Assay Execution and Analysis | $4,887 |
| DGH-031 | 1 probe assay, 500 cells per sample, Assay Execution and Analysis | $5,553 |
| DGH-032 | 1 probe assay, 600 cells per sample, Assay Execution and Analysis | $7,496 |
| DGH-033 | 2 probe assay, 20 cells per sample, Assay Execution and Analysis | $1,341 |
| DGH-034 | 2 probe assay, 50 cells per sample, Assay Execution and Analysis | $2,011 |
| DGH-035 | 2 probe assay, 100 cells per sample, Assay Execution and Analysis | $3,016 |
| DGH-005 | 2 probe assay, 200 cells per sample, Assay Execution and Analysis | $4,525 |
| DGH-055 | 2 probe assay, 400 cells per sample, Assay Execution and Analysis | $5,375 |
| DGH-036 | 2 probe assay, 500 cells per sample, Assay Execution and Analysis | $6,108 |
| DGH-037 | 2 probe assay, 600 cells per sample, Assay Execution and Analysis | $8,246 |
| DGH-038 | 3 probe assay, 20 cells per sample, Assay Execution and Analysis | $1,475 |
| DGH-023 | 3 probe assay, 50 cells per sample, Assay Execution and Analysis | $2,212 |
| DGH-022 | 3 probe assay, 100 cells per sample, Assay Execution and Analysis | $3,318 |
| DGH-004 | 3 probe assay, 200 cells per sample, Assay Execution and Analysis | $4,977 |
| DGH-056 | 3 probe assay, 400 cells per sample, Assay Execution and Analysis | $5,913 |
| DGH-039 | 3 probe assay, 500 cells per sample, Assay Execution and Analysis | $6,719 |
| DGH-040 | 3 probe assay, 600 cells per sample, Assay Execution and Analysis | $9,071 |
| DGH-015 | 4 probe assay, 20 cells per sample, Assay Execution and Analysis | $1,622 |
| DGH-016 | 4 probe assay, 50 cells per sample, Assay Execution and Analysis | $2,433 |
| DGH-041 | 4 probe assay, 100 cells per sample, Assay Execution and Analysis | $3,650 |
| DGH-003 | 4 probe assay, 200 cells per sample, Assay Execution and Analysis | $5,475 |
| DGH-052 | 4 probe assay, 400 cells per sample, Assay Execution and Analysis | $6,500 |
| DGH-042 | 4 probe assay, 500 cells per sample, Assay Execution and Analysis | $7,391 |
| DGH-043 | 4 probe assay, 600 cells per sample, Assay Execution and Analysis | $9,978 |
| DGH-061 | 5 probe assay, 20 cells per sample, Assay Execution and Analysis | $3,268 |
| DGH-053 | 5 probe assay, 100 cells per sample, Assay Execution and Analysis | $4,952 |
| DGH-044 | 5 probe assay, 200 cells per sample, Assay Execution and Analysis | $7,391 |
| DGH-042 | 5 probe assay, 400 cells per sample, Assay Execution and Analysis | $8,795 |
| DGH-058 | 5 probe assay, 500 cells per sample, Assay Execution and Analysis | $10,026 |
| DGH-059 | 5 probe assay, 600 cells per sample, Assay Execution and Analysis | $13,335 |