dGH in-Site™ Targeted Assay Services
dGH in-Site™

Examine Edits One Cell at a Time

dGH in-Site™ gives researchers the ability to directly visualize and characterize rearrangements at their edit sites. Using synthetic oligo probes and repeat-free bioinformatic design, dGH in-Site is capable of tracking edit site translocations, inversions, copy number variants, viral integrations and other complex rearrangements with an ≈2kb resolution.

As an orthogonal analysis to PCR/sequencing techniques, dGH in-Site™ assays enable, through direct visualization, definitive measurement of the presence or absence of inserts. This includes genome-wide distribution and orientation of transgenes or inserted segments. When used in combination with our targeted probes and chromosome paints, dGH in-Site™ assays can provide quantitative, single cell on- vs. off-target outcomes of the delivery and editing process, and can be used to track the stability of the edited genome in both clonal isolates and non-clonal populations.

Concerns over a safe edit site? dGH in-Site™ allows researchers to examine their edits one cell at a time without having to worry about PCR biases or misrepresentative sequencing averages from heterogeneous cell populations. An orthogonal and complementary technique dGH in-Site™ to PCR/sequencing techniques helps provide the most comprehensive data available.

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Ordering Information

CATALOG
PRODUCTS
LIST PRICE
DGH-001 in-Site Adherent/Suspension Culture Development: Thaw, recovery, and harvest optimization $1,000.00
DGH-002 in-Site Standard Probe Production: Design and verification of standard probes $1,100.00
DGH-003 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 200 cells counted per sample $7,775.00
DGH-004 in-Site Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 200 cells counted per sample $5,742.00
DGH-005 in-Site Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 200 cells counted per sample $4,642.00
DGH-006 in-Site Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 200 cells counted per sample $3,542.00
DGH-007 in-Site Custom Probe Production: Design and verification of custom probes $5,500.00
DGH-008 in-Site Adherent/Suspension Metaphase Prep and Harvest $1,000.00
DGH-009 in-Site T-Cell Culture Development: Thaw, recovery, and harvest optimization $1,200.00
DGH-010 in-Site IPSC Cell Culture Development: Thaw, recovery, and harvest optimization $1,300.00
DGH-011 in-Site Whole Blood Culture Development: Thaw, recovery, and harvest optimization $900.00
DGH-012 in-Site T Cells Metaphase Prep and Harvest $1,200.00
DGH-013 in-Site IPSC Metaphase Prep and Harvest $1,300.00
DGH-014 in-Site Whole Blood Metaphase Prep and Harvest $900.00
DGH-015 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 20 cells counted per sample $1,166.25
DGH-016 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 50 cells counted per sample $2,429.69
DGH-017 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 20 cells counted per sample with two quadrants per slide $758.06
DGH-018 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 50 cells counted per sample with two quadrants per slide $1,579.30
DGH-019 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 20 cells counted per sample with four quadrants per slide $492.74
DGH-020 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 50 cells counted per sample with four quadrants per slide $1,026.54

Inquire

INQUIRE

RESOURCES

dGH in-Site™ Data Sheet
dGH in-Site™ Overview
Geno Toxicity and Genomic Instability Datasheet
Sample Gene Editing Report
ACC GENE EDITING POSTER

PRODUCTS

Centromere Pinpoint FISH™ Probes
subTelomere Pinpoint FISH™ Probes
ONCOLOGY PINPOINT FISH™ PROBES
PINPOINT FISH™ TP53/CEP17 KIT
HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
dGH™ CELL PREP KIT
FISH BUFFERS

SERVICES

Cell Culture Services
G-Banding
DGH IN-SITE™ TARGETED ASSAY SERVICES
DGH SCREEN™ UNBIASED ASSAY SERVICES
PINPOINT FISH™ ASSAY SERVICES