dGH in-Site gives researchers the ability to directly visualize and characterize rearrangements at their edit sites. Using synthetic oligo probes and repeat-free bioinformatic design, dGH in-Site is capable of tracking edit site translocations, inversions, copy number variants, viral integrations and other complex rearrangements with an approximate 2kb resolution.
In-site allows researchers to examine their edits one cell at a time without having to worry about PCR biases or misrepresentative sequencing averages from heterogeneous cell populations. Instead, as an orthogonal and complementary technique, in-Site helps provide the most comprehensive data available to answer the question that matters most – is my edit safe?
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