dGH in-Site™ Targeted Assay Services
dGH in-Site™ Assays

Track your genome editing outcomes and get a comprehensive analysis of your on- and off-target effects.

kromatid dGH in-site

Above Fig.: dGH in-Site™ assay in an edited iPSC line cell with no off-target insertions. Target site bracketing probes in green and insert probe in yellow zoomed in and expanded on the right. Results from this sample indicated that 6% of cells had no off-target insertions.

Detect and Differentiate any Genomic Target Including Inversions Starting at 2kb.

For gene therapy applications analysis of specific edits or engineered cell lines are measured for any structural variation involved with the edit site, including rearrangements involving on-target and off-target loci. use dGH in-Site™ to track and locate transgene integration throughout the genome.

Key benefits of dGH in-Site™ assays: 

  • Track transgenes and define Insertional Copy Number (ICN).
  • On- and off-target Insertional Copy Number (ICN).
  • Characterize structural variations from mis-repair of your edit sites.
  • Distribution of integrations on both a single cell and genome-wide basis.
  • Customized to meet individual genomic structural research needs unique to your project.
  • We can design 1-4 probe assays, including assay execution and analysis as many as 600 cells per sample
  • Metaphase prep and harvest, along with cell culture development is available.

Contact us below to receive a quote on a custom project to suit your needs!

Catalog Number
Services
Cost
DGH-002 Standard Probe Production: Design and verification of standard probes $1,375
DGH-007 Custom Probe Production: Design and verification of custom probes $6,250
DGH-009 T-Cell Culture Development: Thaw, recovery, and harvest optimization $1,500
DGH-012 T-Cell Metaphase Prep and Harvest $1,500
DGH-010 IPSC Cell Culture Development: Thaw, recovery, and harvest optimization $1,625
DGH-013 IPSC Metaphase Prep and Harvest $1,625
DGH-011 Whole Blood Culture Development: Thaw, recovery, and harvest optimization $1,125
DGH-014 Whole Blood Metaphase Prep and Harvest $1,125
DGH-029 NK Cell Culture Development: Thaw, recovery, and harvest optimization $1,500
DGH-024 NK Cells Metaphase Prep and Harvest $1,500
DGH-030 1 probe assay, 20 cells per sample, Assay Execution and Analysis $1,219
DGH-027 1 probe assay, 50 cells per sample, Assay Execution and Analysis $1,828
DGH-025 1 probe assay, 100 cells per sample, Assay Execution and Analysis $2,742
DGH-006 1 probe assay, 200 cells per sample, Assay Execution and Analysis $4,113
DGH-054 1 probe assay, 400 cells per sample, Assay Execution and Analysis $4,887
DGH-031 1 probe assay, 500 cells per sample, Assay Execution and Analysis $5,553
DGH-032 1 probe assay, 600 cells per sample, Assay Execution and Analysis $7,496
DGH-033 2 probe assay, 20 cells per sample, Assay Execution and Analysis $1,341
DGH-034 2 probe assay, 50 cells per sample, Assay Execution and Analysis $2,011
DGH-035 2 probe assay, 100 cells per sample, Assay Execution and Analysis $3,016
DGH-005 2 probe assay, 200 cells per sample, Assay Execution and Analysis $4,525
DGH-055 2 probe assay, 400 cells per sample, Assay Execution and Analysis $5,375
DGH-036 2 probe assay, 500 cells per sample, Assay Execution and Analysis $6,108
DGH-037 2 probe assay, 600 cells per sample, Assay Execution and Analysis $8,246
DGH-038 3 probe assay, 20 cells per sample, Assay Execution and Analysis $1,475
DGH-023 3 probe assay, 50 cells per sample, Assay Execution and Analysis $2,212
DGH-022 3 probe assay, 100 cells per sample, Assay Execution and Analysis $3,318
DGH-004 3 probe assay, 200 cells per sample, Assay Execution and Analysis $4,977
DGH-056 3 probe assay, 400 cells per sample, Assay Execution and Analysis $5,913
DGH-039 3 probe assay, 500 cells per sample, Assay Execution and Analysis $6,719
DGH-040 3 probe assay, 600 cells per sample, Assay Execution and Analysis $9,071
DGH-015 4 probe assay, 20 cells per sample, Assay Execution and Analysis $1,622
DGH-016 4 probe assay, 50 cells per sample, Assay Execution and Analysis $2,433
DGH-041 4 probe assay, 100 cells per sample, Assay Execution and Analysis $3,650
DGH-003 4 probe assay, 200 cells per sample, Assay Execution and Analysis $5,475
DGH-052 4 probe assay, 400 cells per sample, Assay Execution and Analysis $6,500
DGH-042 4 probe assay, 500 cells per sample, Assay Execution and Analysis $7,391
DGH-043 4 probe assay, 600 cells per sample, Assay Execution and Analysis $9,978
DGH-061 5 probe assay, 20 cells per sample, Assay Execution and Analysis $3,268
DGH-053 5 probe assay, 100 cells per sample, Assay Execution and Analysis $4,952
DGH-044 5 probe assay, 200 cells per sample, Assay Execution and Analysis $7,391
DGH-042 5 probe assay, 400 cells per sample, Assay Execution and Analysis $8,795
DGH-058 5 probe assay, 500 cells per sample, Assay Execution and Analysis $10,026
DGH-059 5 probe assay, 600 cells per sample, Assay Execution and Analysis $13,335