Screen Your Genome Editing Results with dGH in-Site™ Assays
Let our experts evaluate your genome editing outcomes with KromaTiD’s proprietary directional Genome Hybridization™ (dGH) single-cell assays. dGH provides the highest resolution and lowest limit of detection available for inversions, translocations and other structural variants.
dGH in-Site™ is a single-cell technique comparing pre- and post-cell engineering outcomes that provides the most detailed measure of structural heterogeneity available.
Using dGH in-Site™, we can track the structural variants that may impact your CAR T program most: rearrangements to TRAC and B2M loci, on-and off-target insertions of your transgenes including insertions at potentially genotoxic or oncogenic off-target sites, and indications of stability or instability.
Key benefits of dGH in-Site™ Assay Services
- Track and locate transgenes and DNA cassettes as small as 2kb
- Available for any sequenced mammalian genome including human, animal models and bio-production cell lines
- We provide you a detailed report of metrics and images including
- On- and off-target integrational copy number
- Insert site scoring summary, cells with events
- Example structural variant images
- Distribution of integrations on both a single cell and genome-wide basis
Learn more about dGH in-Site™ technology.
Ordering Information
CATALOG |
PRODUCTS |
LIST PRICE |
|---|---|---|
| DGH-001 | in-Site Adherent/Suspension Culture Development: Thaw, recovery, and harvest optimization | $1,250.00 |
| DGH-002 | in-Site Standard Probe Production: Design and verification of standard probes | $1,155.00 |
| DGH-003 | in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 200 cells counted per sample | $8,163.75 |
| DGH-004 | in-Site Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 200 cells counted per sample | $6029.10 |
| DGH-005 | in-Site Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 200 cells counted per sample | $4,874.10 |
| DGH-006 | in-Site Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 200 cells counted per sample | $3,719.00 |
| DGH-007 | in-Site Custom Probe Production: Design and verification of custom probes | $6,250.00 |
| DGH-008 | in-Site Adherent/Suspension Metaphase Prep and Harvest | $1,250.00 |
| DGH-009 | in-Site T-Cell Culture Development: Thaw, recovery, and harvest optimization | $1,500.00 |
| DGH-010 | in-Site IPSC Cell Culture Development: Thaw, recovery, and harvest optimization | $1,625.00 |
| DGH-011 | in-Site Whole Blood Culture Development: Thaw, recovery, and harvest optimization | $1,125.00 |
| DGH-012 | in-Site T Cells Metaphase Prep and Harvest | $1,500.00 |
| DGH-013 | in-Site IPSC Metaphase Prep and Harvest | $1,625.00 |
| DGH-014 | in-Site Whole Blood Metaphase Prep and Harvest | $1,125.00 |
| DGH-015 | in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 20 cells counted per sample | $1,224.56 |
| DGH-016 | in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 50 cells counted per sample | $2,551.17 |
| DGH-017 | in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 20 cells counted per sample with two quadrants per slide | $795.97 |
| DGH-018 | in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 50 cells counted per sample with two quadrants per slide | $1,658.26 |
| DGH-019 | in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 20 cells counted per sample with four quadrants per slide | $517.38 |
| DGH-020 | in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 50 cells counted per sample with four quadrants per slide | $1,077.87 |
| DGH-021 | dGH in-Site™ Whole Blood Metaphase Prep – Elongated | $1,687.50 |
| DGH-022 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 100 cells counted per sample | $3,738.04 |
| DGH-023 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 50 cells counted per sample | $1,869.02 |
| DGH-024 | dGH in-Site™ NK Cells Metaphase Prep and Harvest | $1,500.00 |
| DGH-025 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 100 cells counted per sample | $1,007.50 |
| DGH-026 | dGH in-Site™ Calibration per sample | $2,062.50 |
| DGH-027 | dGH in-Site™ Assay Execution and Analysis: Imaging and Scoring for 1 probe assay, 50 cells per sample | $1,875.00 |
| DGH-028 | dGH in-Site™ QC one timepoint test per sample | $625.00 |
| DGH-029 | dGH in-Site™ NK Cell Culture Development: Thaw, recovery, and harvest optimization | $1,500.00 |
| DGH-030 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 20 cells counted per sample | $1,218.75 |
| DGH-031 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 500 cells counted per sample | $5,552.93 |
| DGH-032 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 600 cells counted per sample | $7,496.46 |
| DGH-033 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 20 cells counted per sample | $1,340.63 |
| DGH-034 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 50 cells counted per sample | $2,010.94 |
| DGH-035 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 100 cells counted per sample | $3,016.41 |
| DGH-036 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 500 cells counted per sample | $6,108.22 |
| DGH-037 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 600 cells counted per sample | $8,246.10 |
| DGH-038 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 20 cells counted per sample | $1,474.69 |
| DGH-039 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 500 cells counted per sample | $6,719.04 |
| DGH-040 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 600 cells counted per sample | $9.070.71 |
| DGH-041 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 100 cells counted per sample | $3,649.85 |
| DGH-042 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 500 cells counted per sample | $7,390.95 |
| DGH-043 | dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 600 cells counted per sample | $9,977.78 |