dGH in-Site™ Targeted Assay Services
Screen Your Genome Editing Results with dGH in-Site™ Assays

Let our experts evaluate your genome editing outcomes with KromaTiD’s proprietary directional Genome Hybridization™ (dGH) single-cell assays.  dGH provides the highest resolution and lowest limit of detection available for inversions, translocations and other structural variants.  

dGH in-Site™ is a single-cell technique comparing pre- and post-cell engineering outcomes that provides the most detailed measure of structural heterogeneity available.

Using dGH in-Site™, we can track the structural variants that may impact your CAR T program most: rearrangements to TRAC and B2M loci, on-and off-target insertions of your transgenes including insertions at potentially genotoxic or oncogenic off-target sites, and indications of stability or instability.

Key benefits of dGH in-Site™ Assay Services 

  • Track and locate transgenes and DNA cassettes as small as 2kb
  • Available for any sequenced mammalian genome including human, animal models and bio-production cell lines 
  • We provide you a detailed report of metrics and images including 
    • On- and off-target integrational copy number 
    • Insert site scoring summary, cells with events
    • Example structural variant images
    • Distribution of integrations on both a single cell and genome-wide basis

Learn more about dGH in-Site™ technology.

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Ordering Information

CATALOG
PRODUCTS
LIST PRICE
DGH-001 in-Site Adherent/Suspension Culture Development: Thaw, recovery, and harvest optimization $1,250.00
DGH-002 in-Site Standard Probe Production: Design and verification of standard probes $1,155.00
DGH-003 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 200 cells counted per sample $8,163.75
DGH-004 in-Site Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 200 cells counted per sample $6029.10
DGH-005 in-Site Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 200 cells counted per sample $4,874.10
DGH-006 in-Site Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 200 cells counted per sample $3,719.00
DGH-007 in-Site Custom Probe Production: Design and verification of custom probes $6,250.00
DGH-008 in-Site Adherent/Suspension Metaphase Prep and Harvest $1,250.00
DGH-009 in-Site T-Cell Culture Development: Thaw, recovery, and harvest optimization $1,500.00
DGH-010 in-Site IPSC Cell Culture Development: Thaw, recovery, and harvest optimization $1,625.00
DGH-011 in-Site Whole Blood Culture Development: Thaw, recovery, and harvest optimization $1,125.00
DGH-012 in-Site T Cells Metaphase Prep and Harvest $1,500.00
DGH-013 in-Site IPSC Metaphase Prep and Harvest $1,625.00
DGH-014 in-Site Whole Blood Metaphase Prep and Harvest $1,125.00
DGH-015 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 20 cells counted per sample $1,224.56
DGH-016 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 50 cells counted per sample $2,551.17
DGH-017 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 20 cells counted per sample with two quadrants per slide $795.97
DGH-018 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 50 cells counted per sample with two quadrants per slide $1,658.26
DGH-019 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 20 cells counted per sample with four quadrants per slide $517.38
DGH-020 in-Site Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 50 cells counted per sample with four quadrants per slide $1,077.87
DGH-021 dGH in-Site™ Whole Blood Metaphase Prep – Elongated $1,687.50
DGH-022 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 100 cells counted per sample $3,738.04
DGH-023 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 50 cells counted per sample $1,869.02
DGH-024 dGH in-Site™ NK Cells Metaphase Prep and Harvest $1,500.00
DGH-025 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 100 cells counted per sample $1,007.50
DGH-026 dGH in-Site™ Calibration per sample $2,062.50
DGH-027 dGH in-Site™ Assay Execution and Analysis: Imaging and Scoring for 1 probe assay, 50 cells per sample $1,875.00
DGH-028 dGH in-Site™ QC one timepoint test per sample $625.00
DGH-029 dGH in-Site™ NK Cell Culture Development: Thaw, recovery, and harvest optimization $1,500.00
DGH-030 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 20 cells counted per sample $1,218.75
DGH-031 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 500 cells counted per sample $5,552.93
DGH-032 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 1 probe assay, 600 cells counted per sample $7,496.46
DGH-033 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 20 cells counted per sample $1,340.63
DGH-034 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 50 cells counted per sample $2,010.94
DGH-035 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 100 cells counted per sample $3,016.41
DGH-036 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 500 cells counted per sample $6,108.22
DGH-037 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 2 probe assay, 600 cells counted per sample $8,246.10
DGH-038 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 20 cells counted per sample $1,474.69
DGH-039 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 500 cells counted per sample $6,719.04
DGH-040 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 3 probe assay, 600 cells counted per sample $9.070.71
DGH-041 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 100 cells counted per sample $3,649.85
DGH-042 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 500 cells counted per sample $7,390.95
DGH-043 dGH in-Site™ Assay Execution and Analysis: Imaging and scoring for 4 probe assay, 600 cells counted per sample $9,977.78

Please fill out the form below to inquire about dGH in-Site™ assays

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NEW OFFERING

PLASMID MANUFACTURING
DEMACOLCINE (COLCEMID™)

RESOURCES

Buffers and Reagents
dGH in-Site™ Data Sheet
dGH in-Site™ Assay Services Overview

DATASHEETS

Geno Toxicity and Genomic Instability Datasheet

SAMPLE DATA REPORTS

Sample dGH in-Site™ Gene Editing Report

POSTERS

ACC dGH in-Site™ GENE EDITING POSTER

FISH PROBES AND SERVICES

Centromere Pinpoint FISH™ Probes
subTelomere Pinpoint FISH™ Probes
ONCOLOGY PINPOINT FISH™ PROBES
PINPOINT FISH™ TP53/CEP17 KIT
HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
PINPOINT FISH™ ASSAY SERVICES

GENOMIC ASSAY PRODUCTS AND SERVICES

dGH™ CELL PREP KIT
DGH SCREEN™ UNBIASED ASSAY SERVICES
DGH IN-SITE™ TARGETED ASSAY SERVICES

RESEARCH SERVICES

Cell Culture Services
G-Banding