dGH in-Site™ Targeted Assay Services
dGH in-Site™

Examine Edits One Cell at a Time

dGH in-Site™ gives researchers the ability to directly visualize and characterize rearrangements at their edit sites. Using synthetic oligo probes and repeat-free bioinformatic design, dGH in-Site is capable of tracking edit site translocations, inversions, copy number variants, viral integrations and other complex rearrangements with an ≈2kb resolution.

As an orthogonal analysis to PCR/sequencing techniques, dGH in-Site™ assays enable, through direct visualization, definitive measurement of the presence or absence of inserts. This includes genome-wide distribution and orientation of transgenes or inserted segments. When used in combination with our targeted probes and chromosome paints, dGH in-Site™ assays can provide quantitative, single cell on- vs. off-target outcomes of the delivery and editing process, and can be used to track the stability of the edited genome in both clonal isolates and non-clonal populations.

Concerns over a safe edit site? dGH in-Site™ allows researchers to examine their edits one cell at a time without having to worry about PCR biases or misrepresentative sequencing averages from heterogeneous cell populations. An orthogonal and complementary technique dGH in-Site™ to PCR/sequencing techniques helps provide the most comprehensive data available.

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Ordering Information

Products
List Price
Non-refundable set-up fee (when applicable) Project Specific
Assay, execution, imaging, and scoring  (1 Probe) $3,220/sample
Assay, execution, imaging, and scoring: Additional Probes $1,000/probe
Custom Probes (Design and Verification) $5,000/probe
Standard Probe Production $1,000/probe
Culture Development $500/sample
Cell Culture + Harvest $500/sample

Inquire

INQUIRE

RESOURCES

dGH in-Site™ Data Sheet
dGH in-Site™ Overview
Geno Toxicity and Genomic Instability Datasheet
Sample Gene Editing Report
ACC GENE EDITING POSTER

PRODUCTS

Centromere Pinpoint FISH™ Probes
subTelomere Pinpoint FISH™ Probes
ONCOLOGY PINPOINT FISH™ PROBES
PINPOINT FISH™ TP53/CEP17 KIT
HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
dGH™ CELL PREP KIT
FISH BUFFERS

SERVICES

Cell Culture Services
G-Banding
DGH IN-SITE™ TARGETED ASSAY SERVICES
DGH SCREEN™ UNBIASED ASSAY SERVICES
PINPOINT FISH™ ASSAY SERVICES