Pinpoint FISH Kit
Pinpoint FISH™ Kits

oligonucleotide-Based FISH assay

The Pinpoint FISH™ TP53/CEP17 probe kit is an oligonucleotide-based FISH assay. These probes are designed to provide a higher signal-to-noise ratio compared to BAC FISH probes. Delivering improved specificity and hybridization in standard FISH assays.

With KromaTiD’s probe kit you can easily detect mutations with variable breakpoints free of repetitive sequences, providing robust performance bright signals, and consistent hybridization quality without the need for Cot-1 DNA Blocking.

Probe Specification
TP53, 17p13. Red
17q11.1-q11.2, Green

The probe mix consists of a 500kb TP53 probe, labeled in red, that covers the whole TP53 gene and the flanking regions. The probe mix also contains a control probe targeting the 17q11.1-q11.2 region labeled in green.

The Pinpoint FISH™ TP53/CEP 17 FISH Probe Kit is intended to detect the copy number of the LSI TP53 probe target located at 17p13 and of the 17q11.1-q11.2 locus. The approximately 500kb TP53 probe contains the complete TP53 gene and is located at 17p13. The CEP 17 probe is a control probe which hybridizes to the 17q11.1-q11.2 locus.

KromaTiD’s Pinpoint FISH™ TP53/CEP17 Kit is ideal for the following FISH applications:

  • Screening of hematological and other cell suspension samples
  • Testing of indications including, CLL, PLL, LPD and myeloma

Pinpoint FISH™ probes routinely detect targets smaller than BAC FISH probes.  For labs that currently run FISH on hematological and other suspension cell samples, the TP53/CEP17 Assay Kit uses standard FISH consumables and standard FISH equipment. Probes have been tested in combination assays with BAC FISH probes and can work in the same assays.

Ordering Information

SKU
PRODUCT
SIZE
LIST PRICE
PPF053-A  TP53/CEP17 KIT 10 Assays $180

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RESOURCES

Pinpoint FISH™ TP53/CEP17 kit Data Sheet
Pinpoint FISH™ TP53/CEP17 KIT Protocol
Pinpoint FISH™ TP53/CEP17 MSDS
PINPOINT FISH™ PRODUCT BROCHURE
Microscope Assay Specifications datasheet
DNA Probes Oligo Datasheet

PRODUCTS

Centromere Pinpoint FISH™ Probes
subTelomere Pinpoint FISH™ Probes
ONCOLOGY PINPOINT FISH™ PROBES
PINPOINT FISH™ TP53/CEP17 KIT
HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
dGH™ CELL PREP KIT
FISH BUFFERS

SERVICES

Cell Culture Services
G-Banding
DGH IN-SITE™ TARGETED ASSAY SERVICES
DGH SCREEN™ UNBIASED ASSAY SERVICES
PINPOINT FISH™ ASSAY SERVICES