Webinar: dGH™ The Next-Generation of Metaphase FISH Techniques
CAR-T cells, or chimeric antigen receptor T cells, hold great potential for the treatment of cancer and other diseases. Although several CAR-T therapies have received [...]
Gene editing technologies like transcription activator-like effector nucleases (TALEN), zinc finger nucleases (ZFN), CRISPR-Cas systems, base editors, and prime editors, among others, have become essential [...]
Fluorescence In Situ Hybridization (FISH) is a molecular genetics assay which is often employed alongside G-banding (Giemsa banding) for detection and characterization of genomic aberrations. [...]
ABSTRACT Structural variants, such as inversions and translocations, are common by-products of CAR T-cell engineering processes such as CRISPR-Cas9 editing. These variants are formed [...]
Longmont, CO March 27, 2023 – KromaTiD, a single-cell analysis life science tools company focused on the research, development, and commercialization of technology solutions for [...]
Chimeric antigen receptor (CAR) constructs are purpose-built transmembrane proteins artificially added to immune cells, principally T cells, to enhance their ability to find and fight [...]
The design and manufacture of chimeric antigen receptor (CAR) T cells is fraught with complex hurdles. Some of these are encountered during production while others [...]
The pace at which autologous CAR-T cells can be manufactured has been an obstacle for this very powerful technology from the start. Producing a cutting-edge [...]
Download KromaTiD's March 13, 2023 Webinar Simultaneous Mapping of-On and -Off Target Measurements of Structural Variants, Insertions and Translocations in Engineered CAR-T Cells. Download [...]